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Research programme: antibody targeted amanitin conjugates - Heidelberg Pharma AG/Dianthus Therapeutics

Drug Profile

Research programme: antibody targeted amanitin conjugates - Heidelberg Pharma AG/Dianthus Therapeutics

Alternative Names: Anti CD45 amanitin ADC; Anti CD45 amanitin ADC - Dianthus Therapeutics; C 100 programme; C 200 programme - Dianthus Therapeutics; C 300 programme - Dianthus Therapeutics; C200 program - Dianthus Therapeutics; C300 program - Dianthus Therapeutics

Latest Information Update: 09 Oct 2023

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At a glance

  • Originator Heidelberg Pharma AG
  • Developer Dianthus Therapeutics
  • Class Antineoplastics; Bicyclic peptides; Drug conjugates; Immunoconjugates; Immunotoxins; Peptides
  • Mechanism of Action RNA polymerase II inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Autoimmune disorders; Haematological malignancies

Most Recent Events

  • 28 Mar 2023 No recent reports of development identified for preclinical development in Autoimmune-disorders in USA
  • 28 Mar 2023 No recent reports of development identified for preclinical development in Haematological-malignancies in USA
  • 31 Dec 2019 Magenta Therapeutics has a patent in Australia, and pending applications in the US and foreign jurisdictions, and pending PCT applications, covering the CD45-ADC programme

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