CTX 471
Alternative Names: CTX-471Latest Information Update: 22 Aug 2025
At a glance
- Originator Adimab
- Developer Compass Therapeutics; Merck & Co
- Class Antineoplastics; Immunotherapies; Monoclonal antibodies
- Mechanism of Action Antibody-dependent cell cytotoxicity; CD137 antigen agonists; T lymphocyte stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Solid tumours
Most Recent Events
- 11 Aug 2025 Compass Therapeutics plans a phase II trial in Solid tumours in in the second half of 2025 (IV, Infusion)
- 21 May 2025 Compass Therapeutics completes a phase-I trial in Solid tumours (Monotherapy, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV, Infusion) (NCT03881488)
- 28 Apr 2025 CTX 471 is covered by patent protection in USA, Taiwan, China, Eurasia, Japan, Korea, Malaysia, Singapore, and New Zealand