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CTX 471

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Drug Profile

CTX 471

Alternative Names: CTX-471

Latest Information Update: 18 Nov 2024

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At a glance

  • Originator Adimab
  • Developer Compass Therapeutics; Merck & Co
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CD137 antigen agonists; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours

Most Recent Events

  • 18 Nov 2024 Phase-I development is ongoing in Solid-tumours (Late-stage disease, Metastatic disease, Monotherapy, Second-line therapy or greater) in USA (IV, Infusion) (NCT03881488)
  • 12 Nov 2024 Updated efficacy data from the phase Ib trial in Solid tumours released by Compass Therapeutics
  • 12 Nov 2024 Compass Therapeutics plans a phase II trial in Solid tumours in mid-2025 (IV, Infusion)

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