Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

Zelquistinel - Syndeio Biosciences

Next Previous
Drug Profile

Zelquistinel - Syndeio Biosciences

Alternative Names: AGN-241751; GATE-251

Latest Information Update: 01 Jan 2026

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Aptinyx
  • Developer AbbVie; Syndeio Biosciences
  • Class Amines; Antidepressants; Antipsychotics; Aza compounds; Esters; Ketones; Small molecules; Spiro compounds
  • Mechanism of Action NMDA receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Major depressive disorder
  • Phase I Schizophrenia

Most Recent Events

  • 17 Dec 2025 Syndeio Biosciences initiates a phase-II trial for Major depressive disorder in USA (PO) (NCT07115329)
  • 11 Aug 2025 Syndeio Biosciences plans a phase-II trial for Major depressive disorder in USA (PO), (NCT07115329)
  • 24 Jul 2025 Syndeio Biosciences initiates in a phase I pharmacokinetic trial in Healthy volunteers in USA (PO, Tablet) (NCT07099989)

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top