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Research programme: integrins alphaVbeta1 and alphaVbeta6 inhibitors - Pliant Therapeutics

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Drug Profile

Research programme: integrins alphaVbeta1 and alphaVbeta6 inhibitors - Pliant Therapeutics

Alternative Names: Alpha-v beta-1/alpha-v beta-6 dual selective inhibitors - Pliant Therapeutics; PLN-1177; PLN-1561; PLN-1705; αvβ1/αvβ6 dual selective inhibitors - Pliant Therapeutics

Latest Information Update: 28 Apr 2023

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At a glance

  • Originator Pliant Therapeutics
  • Class Anti-inflammatories; Antifibrotics; Hepatoprotectants; Small molecules
  • Mechanism of Action Integrin alphavbeta1 inhibitors; Integrin alphaVbeta6 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Idiopathic pulmonary fibrosis; Non-alcoholic steatohepatitis; Primary sclerosing cholangitis

Most Recent Events

  • 28 Apr 2023 No recent reports of development identified for preclinical development in Non-alcoholic-steatohepatitis in USA (PO)
  • 28 Aug 2022 No recent reports of development identified for preclinical development in Idiopathic-pulmonary-fibrosis in USA
  • 28 Aug 2022 No recent reports of development identified for preclinical development in Primary-sclerosing-cholangitis in USA

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