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SPR 719

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Drug Profile

SPR 719

Alternative Names: SPR-719; VXC-486

Latest Information Update: 18 Oct 2024

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At a glance

  • Originator Vertex Pharmaceuticals
  • Developer Spero Therapeutics
  • Class Antibacterials; Antituberculars
  • Mechanism of Action DNA gyrase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Nontuberculous mycobacterium infections
  • No development reported Tuberculosis

Most Recent Events

  • 16 Oct 2024 Antimicrobial data from a preclinical studies in Nontuberculous mycobacterium infections released by Spero Therapeutics
  • 23 Feb 2024 Spero Therapeutics completes a phase I trial in Nontuberculous mycobacterium infections (In volunteers) in USA (PO) (NCT05955586)
  • 01 Aug 2023 Phase-I clinical trials in Nontuberculous mycobacterium infections (In volunteers) in USA (PO) (NCT05955586)

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