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ARCT 032

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Drug Profile

ARCT 032

Alternative Names: ARCT-032; ARTC032; LUNAR CF - Arcturus Theraepeutics; LUNAR-CF; mRNA CFTR therapeutic - Arcturus Therapeutics

Latest Information Update: 11 Mar 2026

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At a glance

  • Originator Arcturus Therapeutics
  • Developer Arcturus Therapeutics; Cystic Fibrosis Foundation Therapeutics
  • Class Antifibrotics; RNA
  • Mechanism of Action Cystic fibrosis transmembrane conductance regulator expression stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cystic fibrosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Cystic fibrosis

Most Recent Events

  • 03 Mar 2026 The safety review committee reviews and approves ARCT 032 to proceed into a 12-week phase II trial
  • 03 Mar 2026 Arcturus Therapeutics plans a 12-week phase II trial for Cystic fibrosis in USA and other countries (Inhalation), in the first half of 2026
  • 22 Oct 2025 Adverse events and efficacy data from a phase II trial in Cystic fibrosis released by Arcturus Therapeutics

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