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ARCT 032

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Drug Profile

ARCT 032

Alternative Names: ARCT-032; ARTC032; LUNAR CF - Arcturus Theraepeutics; LUNAR-CF; mRNA CFTR therapeutic - Arcturus Therapeutics

Latest Information Update: 08 Jan 2025

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At a glance

  • Originator Arcturus Therapeutics
  • Developer Arcturus Therapeutics; Cystic Fibrosis Foundation Therapeutics
  • Class Antifibrotics; RNA
  • Mechanism of Action Cystic fibrosis transmembrane conductance regulator expression stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cystic fibrosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Cystic fibrosis

Most Recent Events

  • 12 Dec 2024 Phase-II clinical trials in Cystic fibrosis in USA (Inhalation) (NCT06747858)
  • 03 Sep 2024 Arcturus Therapeutics receives IND clearance from the FDA for ARCT 032 in Cystic fibrosis
  • 29 Jul 2024 Arcturus Therapeutics completes phase-I trial in Cystic fibrosis (In volunteers) in New Zealand (Inhalation) (NCT05712538)

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