Latozinemab - Alector
Alternative Names: AL-001; GSK-4527223Latest Information Update: 23 Apr 2025
At a glance
- Originator Adimab; Alector
- Developer Alector; GSK
- Class Antidementias; Immunotherapies; Monoclonal antibodies; Neuroprotectants; Recombinant proteins
- Mechanism of Action Sortilin inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase III Amyotrophic lateral sclerosis; Frontotemporal dementia
Most Recent Events
- 31 Dec 2024 Latozinemab - Alector receives Orphan Drug status for Frontotemporal dementia in European Union
- 05 Jun 2024 Alector completes the phase-II INFRONT-2 trial in Frontotemporal dementia in the UK, Germany, Italy, Netherland, Canada and USA (NCT03987295)
- 07 Feb 2024 Latozinemab - Alector receives Breakthrough Therapy status for Frontotemporal dementia in USA