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Compound 451238

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Drug Profile

Compound 451238

Alternative Names: Compound 451238

Latest Information Update: 02 Oct 2021

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At a glance

  • Originator Royal Marsden NHS Foundation Trust
  • Developer Merck KGaA; Royal Marsden NHS Foundation Trust
  • Class Antineoplastics
  • Mechanism of Action Undefined mechanism
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Soft tissue sarcoma

Most Recent Events

  • 08 Apr 2020 Compound 451238 is still in phase I/II trials for Soft tissue sarcoma (Late-stage disease, Second-line therapy or greater, In adults, In the elderly) in United Kingdom (unspecified route) (NCT03602833)
  • 05 Nov 2018 Phase-I/II clinical trials in Soft tissue sarcoma (Late-stage disease, Second-line therapy or greater, In adults, In the elderly) in United Kingdom (unspecified route) (NCT03602833)
  • 29 Jul 2018 Royal Marsden NHS Foundation Trust and Merck KGaA plan a phase I/II trial for Soft-tissue sarcoma (Combination therapy) in United Kingdom (NCT03602833) (EudraCT2017-001316-11)

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