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Seclidemstat - Decoy Therapeutics

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Drug Profile

Seclidemstat - Decoy Therapeutics

Alternative Names: SP-2577; SP-2577 mesylate

Latest Information Update: 28 Jan 2026

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At a glance

  • Originator University of Utah Research Foundation
  • Developer Decoy Therapeutics; M. D. Anderson Cancer Center; The Ivy Brain Tumor Center; Translational Genomics Research Institute
  • Class Antineoplastics; Benzoic acids; Hydrazines; Piperazines; Small molecules
  • Mechanism of Action Lysine specific demethylase 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Ewing's sarcoma
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase I/II Chronic myelomonocytic leukaemia; Ewing's sarcoma; Myelodysplastic syndromes; Myxoid liposarcoma; Sarcoma; Solid tumours
  • Preclinical Small cell lung cancer
  • No development reported Adrenocortical carcinoma; Glioblastoma; Gynaecological cancer

Most Recent Events

  • 28 Jan 2026 No recent reports of development identified for preclinical development in Gynaecological-cancer in USA (PO)
  • 13 Nov 2025 Salarius Pharmaceuticals has merged with Decoy Therapeutics to form Decoy Therapeutics
  • 17 Apr 2025 Pharmacodynamics and adverse event data from the preclinical trial in Cancer released by Salarius Pharmaceuticals

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