Seclidemstat - Salarius Pharmaceuticals
Alternative Names: SP-2577; SP-2577 mesylateLatest Information Update: 28 Jul 2024
At a glance
- Originator University of Utah Research Foundation
- Developer M. D. Anderson Cancer Center; Salarius Pharmaceuticals; The Ivy Brain Tumor Center; Translational Genomics Research Institute
- Class Antineoplastics; Benzoic acids; Hydrazines; Piperazines; Small molecules
- Mechanism of Action Lysine specific demethylase 1 inhibitors
-
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
- Available For Licensing Yes
Highest Development Phases
- Phase I/II Chronic myelomonocytic leukaemia; Ewing's sarcoma; Myelodysplastic syndromes; Myxoid liposarcoma; Sarcoma; Solid tumours
- Preclinical Gynaecological cancer; Small cell lung cancer
- No development reported Adrenocortical carcinoma; Glioblastoma
Most Recent Events
- 28 Jul 2024 No recent reports of development identified for preclinical development in Adrenocortical-carcinoma in USA
- 18 Jun 2024 Updated efficacy and adverse events data from a phase I/II trial in myelodysplastic syndromes and chronic myelomonocytic leukemia released by Salarius Pharmaceuticals
- 28 Jan 2024 No recent reports of development identified for preclinical development in Glioblastoma in USA (PO)