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Trastuzumab botidotin - Klus Pharma

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Drug Profile

Trastuzumab botidotin - Klus Pharma

Alternative Names: A-166

Latest Information Update: 28 Nov 2025

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At a glance

  • Originator Klus Pharma
  • Developer Klus Pharma; Sichuan Kelun-Biotech Biopharmaceutical
  • Class Antineoplastics; Auristatins; Drug conjugates; Immunoconjugates; Immunotoxins; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Apoptosis stimulants; Tubulin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Registered HER2 positive breast cancer
  • Phase I/II Solid tumours
  • No development reported Adenocarcinoma; Colorectal cancer; Non-small cell lung cancer; Urogenital cancer

Most Recent Events

  • 28 Nov 2025 No recent reports of development identified for phase-I development in Adenocarcinoma(Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (Parenteral, Injection)
  • 28 Nov 2025 No recent reports of development identified for phase-I development in Colorectal-cancer(Inoperable/Unresectable, Late-stage disease, Metastatic disease, Recurrent) in China (Parenteral, Injection)
  • 28 Nov 2025 No recent reports of development identified for phase-I development in Non-small-cell-lung-cancer(Inoperable/Unresectable, Late-stage disease, Metastatic disease, Recurrent) in China (IV, Infusion)

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