AUTO 4
Alternative Names: Anti-TRBC1 CAR T-cells - Autolus; AUTO-4; RQR8/aTRBC1 CAR T cells - AutolusLatest Information Update: 28 Apr 2024
At a glance
- Originator University College London
- Developer Autolus
- Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
- Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Phase I/II T-cell lymphoma
Most Recent Events
- 28 Apr 2024 No recent reports of development identified for phase-I development in T-cell-lymphoma(Second-line therapy or greater) in China (IV)
- 12 Dec 2022 Efficacy and safety data from a phase-I/II trial in T-cell lymphoma were released by Autolus Therapeutics
- 10 Dec 2022 Efficacy and adverse event data from the phase I/II LibrA T1 trial in T-cell lymphoma presented at the 64th American Society of Hematology Annual Meeting and Exposition (ASH-Hem-2022)