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NV 5138

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Drug Profile

NV 5138

Alternative Names: NV-5138; SPN 820; SPN-820/821; SPN-821

Latest Information Update: 04 Nov 2024

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At a glance

  • Originator Navitor Pharmaceuticals; X-Chem
  • Developer Navitor Pharmaceuticals; Supernus Pharmaceuticals
  • Class Antidepressants; Pentanoic acids; Small molecules
  • Mechanism of Action MTORC1 protein stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Depressive disorders; Major depressive disorder

Most Recent Events

  • 31 Oct 2024 Updated efficacy and adverse event data from a phase IIa trial in Major depressive disorder released by Supernus Pharmaceuticals
  • 17 Oct 2024 Efficacy and adverse event data from a phase IIa trial in Major depressive disorder released by Supernus Pharmaceuticals
  • 15 Feb 2024 Phase-II clinical trials in Major depressive disorder (Adjunctive treatment) in USA (PO) (NCT06235905)

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