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MK 8527

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Drug Profile

MK 8527

Alternative Names: MK-8527

Latest Information Update: 29 Jul 2025

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At a glance

  • Originator Merck Sharp & Dohme
  • Class Alcohols; Alkynes; Amines; Antiretrovirals; Chlorinated hydrocarbons; Furans; Pyrimidines; Pyrroles; Small molecules
  • Mechanism of Action Nucleoside reverse transcriptase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II HIV-1 infections

Most Recent Events

  • 29 Jul 2025 Chemical structure information added.
  • 21 Jul 2025 Adverse event data from the phase II trial in HIV-1 infection released by Merck
  • 17 Jul 2025 Merck Sharp & Dohme plans a phase III trial for HIV-1 infections (Prevention, In adolescents, In adults) (PO, tablet) in October 2025 (NCT07071623)

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