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Samarium-153 DOTMP - IGL Pharma

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Drug Profile

Samarium-153 DOTMP - IGL Pharma

Alternative Names: 153-Sm-DOTMP; CycloSam; Sm-153-DOTMP; TLX-090; TLX090-Tx

Latest Information Update: 03 Nov 2025

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At a glance

  • Originator IsoTherapeutics
  • Developer IsoTherapeutics; Telix Pharmaceuticals
  • Class Antineoplastics; Radiopharmaceuticals; Small molecules
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Osteosarcoma
  • New Molecular Entity No

Highest Development Phases

  • Phase I Bone metastases
  • Discontinued Osteosarcoma

Most Recent Events

  • 23 Oct 2025 Phase-I clinical trials in Bone metastases (IV) (NCT07197645)
  • 29 Aug 2025 Discontinued - Preclinical for Osteosarcoma in USA (Parenteral) (Telix Pharmaceuticals pipeline, August 2025)
  • 28 May 2025 No recent reports of development identified for phase-I development in Bone metastases(In adolescents, In the elderly, In adults) in USA (Parenteral)

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