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Imvotamab - IGM Biosciences

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Drug Profile

Imvotamab - IGM Biosciences

Alternative Names: CD20 x CD3 bispecific antibody; IGM 2323

Latest Information Update: 24 Jan 2025

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At a glance

  • Originator IGM Biosciences
  • Class Antineoplastics; Antirheumatics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Follicular lymphoma
  • Phase I/II Non-Hodgkin's lymphoma
  • Discontinued Autoimmune disorders; Myositis; Rheumatoid arthritis; Systemic lupus erythematosus

Most Recent Events

  • 24 Jan 2025 Discontinued - Phase-I for Myositis in USA (IV)
  • 24 Jan 2025 Discontinued - Phase-I for Rheumatoid arthritis (Treatment-experienced) in Poland (IV)
  • 24 Jan 2025 Discontinued - Phase-I for Rheumatoid arthritis (Treatment-experienced) in USA (IV)

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