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Carbidopa/oxytriptan - Evecxia

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Drug Profile

Carbidopa/oxytriptan - Evecxia

Alternative Names: EVX-101

Latest Information Update: 28 Oct 2025

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At a glance

  • Originator Evecxia
  • Class Antidepressants; Behavioural disorder therapies; Catecholamines; Hydrazines; Small molecules; Tryptamines
  • Mechanism of Action Decarboxylase inhibitors; Serotonin modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Obsessive-compulsive disorders
  • No development reported Depressive disorders

Most Recent Events

  • 28 Oct 2025 No recent reports of development identified for phase-I development in Depressive disorders(In volunteers) in United Kingdom (PO, Controlled release)
  • 22 Sep 2025 Evecxia plans a proof of concept phase II study for Obsessive-compulsive disorders in 1H 2026 (PO, tablet)
  • 22 Sep 2025 Evecxia plans a small bridging phase I pharmacokinetics (PK) study in healthy volunteers in the second half of 2025 (PO, tablet)

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