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CUE 221

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Drug Profile

CUE 221

Alternative Names: Ascendant-221; CUE-221; UB 221

Latest Information Update: 10 Aug 2026

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At a glance

  • Originator Ascendant Health Sciences; Chinese Academy of Sciences
  • Developer Chinese Academy of Sciences; United BioPharma
  • Class Antiallergics; Monoclonal antibodies; Skin disorder therapies
  • Mechanism of Action IgE receptor antagonists; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Chronic urticaria
  • Clinical Phase Unknown Allergic asthma; Allergic rhinitis; Atopic dermatitis; Food hypersensitivity

Most Recent Events

  • 03 Aug 2026 Cue Biopharma files an IND application with the US FDA for Food hypersensitivity
  • 15 May 2026 Cue Biopharma announces an intention to submit an Investigational New Drug (IND) amendment to the US FDA to expand development into Food hypersensitivity in the second half of 2026
  • 15 May 2026 Cue Biopharma Plans a global phase IIb trial in Food hypersensitivity

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