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OPC 415

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Drug Profile

OPC 415

Alternative Names: Activated integrin β7-targeted CAR-T cell therapy; Anti-MMG49 chimeric antigen receptor T-cell therapy - Osaka University/Otsuka Pharmaceutical; MMG49 CAR-T cell therapy; OPC-415 - Otsuka Pharmaceutical

Latest Information Update: 03 Feb 2021

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At a glance

  • Originator Osaka University
  • Developer Osaka University; Otsuka Pharmaceutical
  • Class CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Multiple myeloma

Most Recent Events

  • 01 Dec 2020 Phase-I/II clinical trials in Multiple myeloma (Second-line therapy or greater) in Japan (Parenteral) (NCT04649073)
  • 22 Aug 2018 Otsuka Pharmaceuticals in-licenses MMG49 CAR-T cell therapy from Osaka University

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