Drug Profile

Research programme: NK cell engager-based antibodies - Affimed/Genentech

Alternative Names: CD16A ROCK-engagers; CD16A-targeting engagers

Latest Information Update: 28 Aug 2025

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At a glance

Originator Affimed Therapeutics; Genentech
Class Antineoplastics; Bispecific antibodies; Immunotherapies
Mechanism of Action Immunologic cytotoxicity; Natural killer cell stimulants

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

28 Aug 2025 No recent reports of development identified for preclinical development in Cancer in Germany (Parenteral)
28 Aug 2025 No recent reports of development identified for preclinical development in Cancer in USA (Parenteral)
28 Aug 2023 Preclinical development is ongoing in Cancer in USA and Germany (Affimed pipeline, August 2023)

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