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SP 16

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Drug Profile

SP 16

Alternative Names: Serpin Peptide 16; SP-16

Latest Information Update: 18 Nov 2025

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At a glance

  • Originator Serpin Pharma
  • Developer Serpin Pharma; Virginia Commonwealth University
  • Class Analgesics; Anti-inflammatories; Anti-ischaemics; Antihyperglycaemics; Cardiovascular therapies; Oligopeptides; Peptides; Serpins; Skin disorder therapies
  • Mechanism of Action Immunomodulators; LDL receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Inflammation; Myocardial infarction; SARS-CoV-2 acute respiratory disease
  • Preclinical Acute kidney injury; Atopic dermatitis; Chronic inflammatory demyelinating polyradiculoneuropathy; Eosinophilic oesophagitis; Neuropathic pain
  • Research Alopecia areata; Pemphigus vulgaris
  • No development reported Diabetes mellitus; Myocardial reperfusion injury

Most Recent Events

  • 06 Nov 2025 Preclinical trials in Neuropathic pain in USA (IV) before November 2025
  • 06 Nov 2025 Pharmacodynamics data from a preclinical trials in Neuropathic pain released by Dogwood Therapeutics
  • 29 Sep 2025 Dogwood Therapeutics and Serpin Pharma agree to co-develop SP 16 for Chemotherapy-induced neuropathic pain

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