SP 16
Alternative Names: Serpin Peptide 16; SP-16Latest Information Update: 06 Oct 2025
At a glance
- Originator Serpin Pharma
- Developer Serpin Pharma; Virginia Commonwealth University
- Class Analgesics; Anti-inflammatories; Anti-ischaemics; Antihyperglycaemics; Cardiovascular therapies; Oligopeptides; Peptides; Serpins; Skin disorder therapies
- Mechanism of Action Immunomodulators; LDL receptor agonists
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I/II Inflammation; Myocardial infarction; SARS-CoV-2 acute respiratory disease
- Preclinical Acute kidney injury; Atopic dermatitis; Chronic inflammatory demyelinating polyradiculoneuropathy; Eosinophilic oesophagitis
- Research Alopecia areata; Neuropathic pain; Pemphigus vulgaris
- No development reported Diabetes mellitus; Myocardial reperfusion injury
Most Recent Events
- 29 Sep 2025 Dogwood Therapeutics and Serpin Pharma agree to co-develop SP 16 for Chemotherapy-induced neuropathic pain
- 29 Sep 2025 Serpin Pharma plans a phase Ib trial for Chemotherapy induced neuropathy in first half of 2026
- 23 May 2024 Serpin Pharma terminates a phase I/II trial in SARS-COV-2 acute respiratory disease in USA (SC), due to lack of patients (NCT05135624)