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ES2B C001

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Drug Profile

ES2B C001

Alternative Names: AV-001 - AdaptVac; ES2B-001; ES2B-C001; ES2B-C001 (HER2-cVLP); HER2-VLP

Latest Information Update: 28 Jul 2025

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At a glance

  • Originator AdaptVac
  • Developer AdaptVac; ExpreS2ion Biotechnologies
  • Class Antineoplastics; Cancer vaccines; Immunotherapies; Virus-like particle vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase I HER2 positive breast cancer

Most Recent Events

  • 23 Jun 2025 ExpreS2ion BioTech anticipated response to protocol amendment in third quarter of 2025
  • 13 May 2025 ExpreS2ion Biotech files protocol amendment to optionally include concurrent administration of a HER2-targeted antibody-drug conjugate in HER2 positive breast cancer
  • 17 Dec 2024 Phase-I clinical trials in HER2-positive-breast-cancer (Metastatic disease, Late-stage disease, Combination therapy) in Austria (Parenteral) (NCT06746688)

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