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Lutetium 177 rosopatamab tetraxetan - Telix Pharmaceuticals

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Drug Profile

Lutetium 177 rosopatamab tetraxetan - Telix Pharmaceuticals

Alternative Names: 177-Lu-DOTA-Rosopatamab - Telix Pharmaceuticals; 177Lu-DOTA-rosopatamab; 177Lu-DOTA-rosopatamb; 177Lu-DOTA-TLX591; 177Lu-DOTA-TLX591-CHO; 177Lu-TLX-591; Lutetium 177 DOTA rosopatamab - Telix Pharmaceuticals; Lutetium 177 rosopatamab - Telix Pharmaceuticals; TLX 591; TLX591t; TX591

Latest Information Update: 27 Aug 2024

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At a glance

  • Originator Telix Pharmaceuticals
  • Class Antineoplastics; Immunoconjugates; Monoclonal antibodies; Radioisotopes; Radiopharmaceuticals
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase III Prostate cancer

Most Recent Events

  • 22 Aug 2024 Phase-III clinical trials in Prostate cancer (Combination therapy, Hormone refractory, Metastatic disease, Second-line therapy or greater) in USA (IV) (NCT04876651)
  • 22 Aug 2024 US FDA approves IND application for Lutetium 177 rosopatamab tetraxetan for phase III ProstACT-GLOBAL trial in Prostate cancer
  • 31 Jul 2024 Telix Pharmaceuticals plans phase III ProstACT-GLOBAL trial in Prostate cancer (Metastatic disease, Hormone refractory, Second-line therapy or greater, Combination therapy) (IV) (NCT06520345)

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