Drug Profile

Research programme: cystinuria therapeutics - Spyre Therapeutics

Alternative Names: AEB-5100; Cystinase - Spyre Therapeutics

Latest Information Update: 24 Oct 2025

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At a glance

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity No

24 Oct 2025 Discontinued - Preclinical for Cystinuria in USA (Parenteral)
24 Oct 2025 Discontinued - Preclinical for Metabolic disorders in USA (Parenteral)
28 Feb 2023 Preclinical trials in Cystinuria in USA (Parenteral) (Aeglea Biotherapeutics pipeline, February 2023)

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