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KUR 501

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Drug Profile

KUR 501

Alternative Names: Anti-GD2 CAR NKT cells; CAR-modified NKT-cell therapy; CAR-NKT therapy; CAR.GD2-IL-15 NKTs; Chimeric antigen receptors natural killer T-cells (CAR-NKT) therapy; CMD-501; GINAKIT Cells; KUR-501; KUR-501 GD2 CAR-NKT

Latest Information Update: 16 Apr 2024

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At a glance

  • Originator Baylor College of Medicine
  • Developer Baylor College of Medicine; Center for Cell and Gene Therapy
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies; NKT cell therapies
  • Mechanism of Action Immunologic cytotoxicity; Interleukin 15 replacements; Natural killer T cell replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Neuroblastoma; Small cell lung cancer

Most Recent Events

  • 12 Sep 2023 Discontinued - Phase-I for Neuroblastoma (In adolescents, In children, In infants, Late-stage disease, Second-line therapy or greater, In adults) in USA (Parenteral)
  • 07 Aug 2023 KUR 501 is still in phase-I development in Neuroblastoma (In adolescents, In children, In infants, Late-stage disease, Second-line therapy or greater, In adults) in USA (Parenteral, Infusion) (Kuur Therapeutics, August 2023)
  • 28 May 2023 No recent reports of development identified for phase-I development in Neuroblastoma(In adolescents, In children, In infants, Late-stage disease, Second-line therapy or greater, In adults) in USA (Parenteral, Infusion)

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