IMA 203
Alternative Names: IMA-203; IMA203-GEN1Latest Information Update: 09 Jun 2025
At a glance
- Originator Immatics US
- Developer Bristol-Myers Squibb; Immatics US; University of Texas M. D. Anderson Cancer Center
- Class Antineoplastics; Gene therapies; Immunotherapies; T lymphocyte cell therapies
- Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
- Available For Licensing Yes
Highest Development Phases
- Phase III Malignant melanoma
- Phase I Solid tumours
- No development reported Haematological malignancies
Most Recent Events
- 31 May 2025 Efficacy and adverse event data from an extended phase Ib portion of phase I ACTengine trial in Solid tumours released by Immatics
- 13 May 2025 Immatics announces intention to submit BLA for Malignant melanoma in first quarter of 2027
- 28 Apr 2025 Immatics in collaboration with Moderna plans a phase I trial for Melanoma and Sarcoma (Metastatic disease, Unresectable/Inoperable, Second-line therapy or greater, Combination therapy) in April 2025 (NCT06946225)