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CYAD 101

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Drug Profile

CYAD 101

Alternative Names: CYAD-101; TIM8-CYAD-01

Latest Information Update: 15 May 2023

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At a glance

  • Originator Celyad
  • Developer Celyad Oncology; Merck Sharp & Dohme
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies; Peptides
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Colorectal cancer

Most Recent Events

  • 31 Dec 2022 Ceylad Oncology terminates clinical trial collaboration agreement with Merck Sharp & Dohme for CYAD 101
  • 12 Oct 2022 Discontinued - Phase-I for Colorectal cancer (Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in Belgium (Parenteral), based on strategic, financial and medical review
  • 12 Oct 2022 Discontinued - Phase-I for Colorectal cancer (Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (Parenteral), based on strategic, financial and medical review

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