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Vociprotafib - REVOLUTION Medicine

Drug Profile

Vociprotafib - REVOLUTION Medicine

Alternative Names: RMC-4630; SAR 442720

Latest Information Update: 25 Jan 2024

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At a glance

  • Originator REVOLUTION Medicines
  • Developer Amgen; Netherlands Cancer Institute; REVOLUTION Medicines; Sanofi; The Lustgarten Foundation
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Protein tyrosine phosphatase non receptor type 11 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Non-small cell lung cancer
  • Phase I/II Colorectal cancer; Solid tumours
  • Phase I Pancreatic cancer

Most Recent Events

  • 23 Jan 2024 Mirati Therapeutics has been acquired by Bristol-Myers Squibb
  • 20 Oct 2023 Pharmacokinetics, efficacy and adverse events data from the phase I/Ib SHERPA trial presented at the 48th European Society for Medical Oncology Congress (ESMO-2023)
  • 27 Feb 2023 REVOLUTION Medicine plans to evaluate RMC-4630 in combination with its RAS(ON) Inhibitors in the future
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