Drug Profile
Vociprotafib - REVOLUTION Medicine
Alternative Names: RMC-4630; SAR 442720Latest Information Update: 25 Jan 2024
Price :
$50
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At a glance
- Originator REVOLUTION Medicines
- Developer Amgen; Netherlands Cancer Institute; REVOLUTION Medicines; Sanofi; The Lustgarten Foundation
- Class Antineoplastics; Small molecules
- Mechanism of Action Protein tyrosine phosphatase non receptor type 11 antagonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Non-small cell lung cancer
- Phase I/II Colorectal cancer; Solid tumours
- Phase I Pancreatic cancer
Most Recent Events
- 23 Jan 2024 Mirati Therapeutics has been acquired by Bristol-Myers Squibb
- 20 Oct 2023 Pharmacokinetics, efficacy and adverse events data from the phase I/Ib SHERPA trial presented at the 48th European Society for Medical Oncology Congress (ESMO-2023)
- 27 Feb 2023 REVOLUTION Medicine plans to evaluate RMC-4630 in combination with its RAS(ON) Inhibitors in the future