Drug Profile
Anti-MUC1 CAR T cell/PD-1 knockout engineered T cell therapy - Guangzhou Anjie Biomedical Technology
Alternative Names: Anti-MUC1 CAR T cells and PD-1 knockout engineered T cells; Anti-MUC1 CAR-T cells combined with PD-1 knockout engineered T cellsLatest Information Update: 07 Jul 2023
Price :
$50
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At a glance
- Originator Guangzhou Anjie Biomedical Technology
- Developer Guangzhou Anjie Biomedical Technology; Sun Yat-Sen University; The First Affiliated Hospital of Guangdong Pharmaceutical University; University of Technology Sydney
- Class CAR-T cell therapies; Gene therapies; Immunotherapies; T lymphocyte cell therapies
- Mechanism of Action Gene silencing; Immunologic cytotoxicity; T lymphocyte replacements
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Phase I/II Breast cancer; Non-small cell lung cancer; Oesophageal cancer
Most Recent Events
- 02 Jun 2023 Efficacy and adverse events data from a phase I/II trial in Oesophageal cancer presented at the 59th Annual Meeting of the American Society of Clinical Oncology (ASCO-2023)
- 16 Nov 2022 Sun Yat-Sen University and Guangzhou Anjie Biomedical Technology complete a phase I/II trial in Breast cancer (Late-stage disease, Recurrent, Second-line therapy or greater, Metastatic disease) in China (Parenteral) (NCT05812326)
- 24 Mar 2021 Phase-I/II development is ongoing in Non-small cell lung cancer and Oesophageal cancer in China (Parenteral)