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Zavegepant - Pfizer

Drug Profile

Zavegepant - Pfizer

Alternative Names: BHV 3500; BMS-742413; BMS-742413-03; Vazegepant; Vazegepant - Pfizer; Zavegepant hydrochloride; ZAVZPRET

Latest Information Update: 05 Jun 2024

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At a glance

  • Originator Bristol-Myers Squibb
  • Developer Pfizer
  • Class Anti-infectives; Antiallergics; Antimigraines; Indazoles; Piperazines; Piperidines; Quinolines; Small molecules
  • Mechanism of Action Calcitonin gene-related peptide receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Migraine
  • Phase II/III COVID-19 respiratory infection
  • Phase I Allergic asthma

Most Recent Events

  • 13 Apr 2024 Adverse events data from a phase II/III trial in Migraine presented at the 76th Annual Meeting of the American Academy of Neurology (AAN-2024)
  • 13 Apr 2024 Drug interactions data from a preclinical studies presented at the 76th Annual Meeting of the American Academy of Neurology 2024 (AAN-2024)
  • 21 Mar 2024 Biohaven Pharmaceuticals terminates a phase II/III trial for Migraine (Prevention, In adults, In the elderly) in March 2021 (PO, Capsule) as per a strategic decision for the adjusted development plan for the drug (NCT04804033)
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