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MDG 1021

Drug Profile

MDG 1021

Alternative Names: HA-1-specific T cell receptor therapy; MDG-1021

Latest Information Update: 19 Oct 2021

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At a glance

  • Originator Leiden University Medical Center
  • Developer Leiden University Medical Center; MediGene AG
  • Class Antineoplastics; Gene therapies; Immunotherapies; T lymphocyte cell therapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Discontinued Haematological malignancies; Solid tumours

Most Recent Events

  • 30 Sep 2021 Medigene withdraws a phase I trial in Haematological malignancies (Second-line therapy or greater) in Netherlands before enrolment due to transfer of rights of MDG 1021 to Miltenyi Biotec (IV) (NCT04464889)
  • 01 Jul 2021 Medigene transfers rights related to MDG 1021 to Miltenyi Biotec
  • 16 May 2021 MDG 1021 is available for licensing as of 11 May 2021

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