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Ixoberogene soroparvovec - Adverum Biotechnologies

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Drug Profile

Ixoberogene soroparvovec - Adverum Biotechnologies

Alternative Names: AAV.7m8-aflibercept; ADVM-022; Ixo-vec

Latest Information Update: 27 May 2025

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At a glance

  • Originator Weill Cornell Medical College
  • Developer Adverum Biotechnologies
  • Class Eye disorder therapies; Gene therapies
  • Mechanism of Action Gene transference; Vascular endothelial growth factor A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase III Wet age-related macular degeneration
  • Phase II Diabetic retinopathy
  • Discontinued Diabetic macular oedema

Most Recent Events

  • 14 May 2025 Efficacy data from the phase I OPTIC trial in Wet age-related macular degeneration released by Adverum Biotechnologies
  • 15 Apr 2025 Adverum Biotechnologies plans phase-III AQUARIUS trial for Wet age-related macular degeneration in 2H 2025 (Intravitreous)
  • 03 Mar 2025 Phase-III clinical trials in Wet age-related macular degeneration (Intravitreous) in USA (NCT06856577)

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