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CD16-IL15-CLEC12A TriKE

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Drug Profile

CD16-IL15-CLEC12A TriKE

Alternative Names: CD16-IL15-CLEC12A Trispecific Killer Engager; CLEC12A TriKE

Latest Information Update: 28 Dec 2022

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At a glance

  • Originator University of Minnesota
  • Developer GT Biopharma; University of Minnesota
  • Class Antineoplastics; Immunoglobulin fragments; Recombinant fusion proteins
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Natural killer cell stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Acute myeloid leukaemia

Most Recent Events

  • 28 Dec 2022 No recent reports of development identified for preclinical development in Acute-myeloid-leukaemia in USA (Parenteral)
  • 07 Dec 2018 Pharmacodynamics data from preclinical study presented at the 60th annual meeting of American Society of Hematology (ASH-2018)
  • 20 Nov 2018 Preclinical trials in Acute myeloid leukaemia in USA (Parenteral) before November 2018

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