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OVV CXCR4 A Fc

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Drug Profile

OVV CXCR4 A Fc

Alternative Names: CXCR4 antagonist armed viral oncotherapy - Roswell Park Cancer Institute Corporation/Tactiva Therapeutics; CXCR4 antagonist-expressing oncolytic vaccinia virus - Roswell Park Cancer Institute Corporation/Tactiva Therapeutics; OVV-CXCR4-A-Fc

Latest Information Update: 28 Nov 2020

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At a glance

  • Originator Roswell Park Cancer Institute
  • Class Antineoplastics; Oncolytic viruses; Recombinant fusion proteins
  • Mechanism of Action Antibody-dependent cell cytotoxicity
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • No development reported Ovarian cancer

Most Recent Events

  • 28 Nov 2020 No recent reports of development identified for preclinical development in Ovarian-cancer in USA (IV)
  • 26 Nov 2018 Preclinical development is ongoing in Ovarian cancer in USA (IV)
  • 26 Nov 2018 Tactiva Therapeutics licenses oncolytic vaccinia virus armed with CXCR4 antagonist from the Roswell Park Cancer Institute Corporation for Ovarian cancer

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