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Nitazoxanide - Genfit

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Drug Profile

Nitazoxanide - Genfit

Alternative Names: G 1090N; NTZ - Genfit; Repurposed nitazoxanide - Genfit

Latest Information Update: 25 Sep 2025

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At a glance

  • Originator Genfit
  • Developer Genfit; Pinnacle Clinical Research
  • Class Amides; Anthelmintics; Anti-inflammatories; Antidiarrhoeals; Antifibrotics; Antiprotozoals; Antivirals; Benzamides; Hepatoprotectants; Nitro compounds; Phenylacetates; Small molecules; Thiazoles
  • Mechanism of Action EIF-2 kinase modulators; HN protein inhibitors; Oxidoreductase inhibitors; Receptor protein-tyrosine kinase modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Hepatic fibrosis
  • No development reported Liver failure

Most Recent Events

  • 22 Sep 2025 Genfit plans a proof of concept clinical trial for Liver Failure in the first half of 2026
  • 07 Aug 2025 Genfit plans a phase I trial for Liver Failure (In volunteers) in August 2025 (PO, Capsules) (NCT07110441)
  • 06 Feb 2025 Genfit plans a clinical trial for Liver failure in the first quarter of 2025

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