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Nitazoxanide - Genfit

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Drug Profile

Nitazoxanide - Genfit

Alternative Names: G-1090N; NTZ - Genfit; Repurposed nitazoxanide - Genfit

Latest Information Update: 18 Mar 2026

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At a glance

  • Originator Genfit
  • Developer Genfit; Pinnacle Clinical Research
  • Class Amides; Anthelmintics; Anti-inflammatories; Antidiarrhoeals; Antifibrotics; Antiprotozoals; Antivirals; Benzamides; Hepatoprotectants; Nitro compounds; Phenylacetates; Small molecules; Thiazoles
  • Mechanism of Action EIF-2 kinase modulators; HN protein inhibitors; Oxidoreductase inhibitors; Receptor protein-tyrosine kinase modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Liver failure
  • New Molecular Entity No

Highest Development Phases

  • Phase II Hepatic fibrosis
  • Phase I Liver failure

Most Recent Events

  • 18 Mar 2026 Phase I development for Liver Failure is underway in USA (PO, Capsules) (NCT07110441) (Genfit pipeline, March 2026)
  • 09 Mar 2026 Nitazoxanide - Genfit receives Orphan Drug status for Liver failure in USA
  • 09 Mar 2026 Genfit plans a phase II trial for Liver failure in the second half of 2026 (PO)

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