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CT 868

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Drug Profile

CT 868

Alternative Names: CT-868; GLP-1/GIP receptor agonist - Carmot Therapeutics; RG-6641

Latest Information Update: 13 May 2024

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At a glance

  • Originator Carmot Therapeutics
  • Class Antihyperglycaemics; Hepatoprotectants; Obesity therapies; Peptides; Small molecules
  • Mechanism of Action Gastric inhibitory polypeptide receptor agonists; Glucagon-like peptide-1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Type 1 diabetes mellitus; Type 2 diabetes mellitus
  • Discontinued Non-alcoholic steatohepatitis

Most Recent Events

  • 09 May 2024 Roche announces intention to submit regulatory application for Type 1 diabetes mellitus in or after 2027 (Roche pipeline, May 2024)
  • 29 Jan 2024 Carmot Therapeutics has been acquired by Roche
  • 15 Nov 2023 Efficacy and adverse events data from a phase II trial in Type 2 diabetes mellitus released by Carmot Therapeutics

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