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CT 868

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Drug Profile

CT 868

Alternative Names: CT-868; GLP-1/GIP receptor agonist - Carmot Therapeutics; RG-6641

Latest Information Update: 07 Aug 2025

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At a glance

  • Originator Carmot Therapeutics
  • Class Antihyperglycaemics; Hepatoprotectants; Obesity therapies; Peptides; Small molecules
  • Mechanism of Action Gastric inhibitory polypeptide receptor agonists; Glucagon-like peptide-1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Type 1 diabetes mellitus; Type 2 diabetes mellitus
  • Discontinued Non-alcoholic steatohepatitis

Most Recent Events

  • 09 Jul 2025 Carmot Therapeutics completes a phase II trial in Type 1 diabetes mellitus (Adjunctive treatment) in USA (SC) (NCT06062069)
  • 29 Apr 2025 Roche announces intention to submit regulatory application for Type 1 diabetes mellitus in or after 2028 (Roche pipeline, April 2025)
  • 06 Apr 2024 Carmot Therapeutics completes a phase I trial in Type 1 diabetes mellitus in USA (SC) (NCT05794581)

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