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Eflimrufusp alfa - RemeGen/Santen Pharmaceutical

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Drug Profile

Eflimrufusp alfa - RemeGen/Santen Pharmaceutical

Alternative Names: RC 28 E; RC28-E injection; STN-1014300; STN-1014301

Latest Information Update: 15 Dec 2025

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At a glance

  • Originator RemeGen; Yantai Rongchang Biological Engineering
  • Developer RemeGen
  • Class Bispecific antibodies; Eye disorder therapies; Recombinant fusion proteins
  • Mechanism of Action Fibroblast growth factor inhibitors; Vascular endothelial growth factor A inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Diabetic macular oedema
  • Phase III Wet age-related macular degeneration
  • Phase II Diabetic retinopathy

Most Recent Events

  • 30 Sep 2025 Preregistration for Diabetic macular oedema in China (Intravitreous) (Santen Pharmaceutical pipeline, December 2025)
  • 19 Aug 2025 Remegen announces intention to submit BLA to NMPA for Diabetic macular edema in second half of 2025
  • 19 Aug 2025 Santen Pharmaceuticals in-licenses RC 28 E from Remegen

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