Drug Profile

Research programme: dual mechanism Na/K channel and SERCA2a activators - Windtree Therapeutics

Alternative Names: Chronic heart failure therapy - Windtree Therapeutics; CV-IST2

Latest Information Update: 20 May 2025

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At a glance

Originator CVie Therapeutics
Developer Windtree Therapeutics
Class Heart failure therapies
Mechanism of Action Sarcoplasmic reticulum calcium-transporting ATPase stimulants

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Preclinical Chronic heart failure

Most Recent Events

12 May 2025 Pharmacodynamics data from preclinical studies in Heart failure released by Windtree Therapeutics
28 Apr 2025 No recent reports of development identified for preclinical development in Chronic-heart-failure in Hong Kong (PO)
01 Feb 2024 Windtree renews agreement with Chang Gung University for SERCA2a research

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