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Research programme: Bcl-xl syntholytics - Dialectic Therapeutics

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Drug Profile

Research programme: Bcl-xl syntholytics - Dialectic Therapeutics

Alternative Names: PROTACs - Dialectic Therapeutics; Proteolysis targeting chimeras - Dialectic Therapeutics

Latest Information Update: 28 Jan 2023

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At a glance

  • Originator University of Florida; University of Texas Health Science Center at San Antonio; University of Texas M. D. Anderson Cancer Center
  • Developer Dialectic Therapeutics; University of Florida; University of Texas Health Science Center at San Antonio; University of Texas M. D. Anderson Cancer Center
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Bcl-X protein inhibitors; Ubiquitin protein ligase modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Cancer

Most Recent Events

  • 28 Jan 2023 No recent reports of development identified for preclinical development in Cancer in USA
  • 07 Dec 2019 Pharmacodynamics data from preclinical trials in Cancer presented at the 61st Annual Meeting and Exposition of the American Society of Hematology (ASH-2019)
  • 01 Dec 2018 Dialectic Therapeutics has patents pending for Bcl-xl syntholytics prior to December 2018

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