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Zodasiran - Arrowhead Pharmaceuticals

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Drug Profile

Zodasiran - Arrowhead Pharmaceuticals

Alternative Names: ARO-ANG3; ARO-ANG33; VSA-003

Latest Information Update: 09 Dec 2024

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At a glance

  • Originator Roche
  • Developer Arrowhead Pharmaceuticals
  • Class Antihyperlipidaemics; Cardiovascular therapies; Small interfering RNA
  • Mechanism of Action ANGPTL3 protein expression inhibitors; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Dyslipidaemias
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Dyslipidaemias; Hyperlipoproteinaemia type II

Most Recent Events

  • 02 Dec 2024 Visirna Therapeutics plans a phase III trial for Hypercholesterolemia (In adolescents, In adults, In the elderly) in China (SC, Injection) (NCT06712771)
  • 24 Sep 2024 Arrowhead Pharmaceuticals completes a phase II trial in Dyslipidaemias in New Zealand, Canada, Australia and USA (SC) (NCT04832971)
  • 30 May 2024 Updated efficacy and adverse event data from a phase IIb ARCHES-2 in Dyslipidaemias released by Arrowhead pharmaceuticals

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