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Research programme: antibody-oligonucleotide conjugates - Avidity Biosciences

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Drug Profile

Research programme: antibody-oligonucleotide conjugates - Avidity Biosciences

Alternative Names: AOC-DMD; AOCs; TfR.mAb-siMSTN

Latest Information Update: 17 Apr 2023

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At a glance

  • Originator Avidity Biosciences
  • Class Drug conjugates; Immunoconjugates; Monoclonal antibodies; Oligonucleotides; Small interfering RNA
  • Mechanism of Action RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Duchenne muscular dystrophy

Most Recent Events

  • 17 Apr 2023 Antibody-oligonucleotide conjugates are still in preclinical trials for Duchenne muscular dystrophy in USA (Parenteral) (Avidity Biosciences pipeline, April 2023)
  • 28 Nov 2022 No recent reports of development identified for preclinical development in Duchenne muscular dystrophy in USA (Parenteral)
  • 15 Mar 2021 Avidity Biosciences plans a clinical trial in Duchenne muscular dystrophy in 2022

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