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Elraglusib - Actuate Therapeutics

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Drug Profile

Elraglusib - Actuate Therapeutics

Alternative Names: 9 ING 41

Latest Information Update: 14 Sep 2026

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At a glance

  • Originator Northwestern University; University of Illinois at Chicago
  • Developer Actuate Therapeutics; Incyte Corporation
  • Class Antineoplastics; Benzofurans; Dioxolanes; Indoles; Pyrroles; Small molecules
  • Mechanism of Action Glycogen synthase kinase 3 beta inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Soft tissue sarcoma; Glioblastoma; Pancreatic cancer; Neuroblastoma; Adenocarcinoma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Adenocarcinoma; Adenoid cystic carcinoma; Myelofibrosis; Neuroblastoma; Pancreatic cancer; Salivary gland cancer
  • Phase I/II Cancer
  • No development reported Brain cancer; Chronic lymphocytic leukaemia; Colorectal cancer

Most Recent Events

  • 09 Sep 2026 Pharmacodynamics data from a preclinical trial in Pancreatic cancer released by Actuate Therapeutics
  • 09 Jun 2026 Phase-I/II clinical trials in Neuroblastoma (In infants, In children, In adolescents, In adults, Combination therapy, Second-line therapy or greater) in United Kingdom (IV) (CTIS2024-516115-24-00)
  • 29 May 2026 Efficacy, adverse events data from a phase II trial in Adenocarcinoma presented at the 62nd Annual Meeting of the American Society of Clinical Oncology (ASCO-2026)

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