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Elraglusib - Actuate Therapeutics

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Drug Profile

Elraglusib - Actuate Therapeutics

Alternative Names: 9 ING 41

Latest Information Update: 09 Jun 2025

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At a glance

  • Originator Northwestern University; University of Illinois at Chicago
  • Developer Actuate Therapeutics; Incyte Corporation
  • Class Antineoplastics; Benzofurans; Dioxolanes; Indoles; Pyrroles; Small molecules
  • Mechanism of Action Glycogen synthase kinase 3 beta inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Glioblastoma; Pancreatic cancer; Soft tissue sarcoma; Neuroblastoma; Adenocarcinoma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Adenoid cystic carcinoma; Myelofibrosis; Neuroblastoma; Pancreatic cancer; Salivary gland cancer
  • Phase I/II Cancer
  • Preclinical Brain cancer; Chronic lymphocytic leukaemia
  • No development reported Colorectal cancer

Most Recent Events

  • 31 May 2025 Efficacy data from a phase I/II trial in Cancer released by Actuate Therapeutics
  • 28 May 2025 No recent reports of development identified for preclinical development in Colorectal-cancer in USA (IV)
  • 26 Mar 2025 Anwaar Saeed plans to initiate a phase I trial for Pancreatic adenocarcinoma (In combination therapy, Late-stage disease, Recurrent, Metastatic disease in the US (Unspecified) (NCT06896188)

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