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Acapatamab - Amgen

Drug Profile

Acapatamab - Amgen

Alternative Names: AMG 160; anti-PSMAxanti-CD3-BiTE; anti-PSMAxanti-CD3-BiTE-bispecific-T-cell-engager

Latest Information Update: 06 Oct 2021

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At a glance

  • Originator Amgen
  • Developer Amgen; BeiGene
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Cytotoxic T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Prostate cancer
  • Phase I Non-small cell lung cancer

Most Recent Events

  • 31 Aug 2021 Phase-I clinical trials in Non-small cell lung cancer (Late-stage disease, Recurrent, Second-line therapy or greater) in Austria (IV) (NCT04822298)
  • 30 Apr 2021 Phase-I clinical trials in Non-small cell lung cancer (Late-stage disease, Recurrent, Second line therapy or greater) in Australia (IV) before April 2021 (Amgen's pipeline, April 2021)
  • 30 Mar 2021 Amgen plans a phase I trial for Non small cell lung cancer (IV) in May 2021 (NCT04822298)
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