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Etavopivat - Forma therapeutics

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Drug Profile

Etavopivat - Forma therapeutics

Alternative Names: FT-4202; NN 7535; NN-7536; NN7535 – Etavopivat in SCD; NN7535 – Etavopivat in Sickle cell disease; NN7536 – Etavopivat in Beta thalassemia

Latest Information Update: 18 Jun 2025

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At a glance

  • Originator FORMA Therapeutics
  • Class Antianaemics; Small molecules
  • Mechanism of Action Pyruvate kinase stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Sickle cell anaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Sickle cell anaemia; Thalassaemia
  • Phase II Myelodysplastic syndromes

Most Recent Events

  • 09 Jun 2025 Novo Nordisk plans a phase I trial (In volunteers) in USA (PO), in June 2025 (NCT07023029)
  • 17 Feb 2025 Phase-III clinical trials in Sickle cell anaemia (In adolescents, In adults, In the elderly) in USA, United Kingdom, Uganda, Turkey, Spain, Saudi Arabia, Oman, Nigeria, Netherlands, Lebanon, Kenya, Italy, India, Greece, Ghana, France, Colombia, Canada, Brazil, Belgium, Australia (PO) (NCT06612268)
  • 07 Feb 2025 Novo Nordisk plans a phase I trial for Healthy volunteers in USA (PO) (NCT06813924)

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