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Etavopivat - Forma therapeutics

Drug Profile

Etavopivat - Forma therapeutics

Alternative Names: FT-4202; NN 7535; NN-7536; NN7535 – Etavopivat in SCD; NN7535 – Etavopivat in Sickle cell disease; NN7536 – Etavopivat in Beta thalassemia

Latest Information Update: 03 Jun 2024

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At a glance

  • Originator FORMA Therapeutics
  • Class Antianaemics; Small molecules
  • Mechanism of Action Pyruvate kinase stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Sickle cell anaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Sickle cell anaemia
  • Phase II Myelodysplastic syndromes; Thalassaemia

Most Recent Events

  • 28 May 2024 Novo Nordisk plans to initiate a pharmacokinetic phase I trial for sickle cell anemia and thalassemia (In volunteers) in the US (NCT06433661)
  • 29 Mar 2024 Novo Nordisk plans a phase I pharmacokinetic trial in USA (PO) (NCT06336018)
  • 07 Aug 2023 Phase-III clinical trials in Sickle cell anaemia (PO) (Novo Nordisk pipeline, August 2023)
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