At a glance
- Originator Syntrix Biosystems
- Developer Boehringer Ingelheim; Bristol-Myers Squibb; National Cancer Institute (USA); Syntrix Biosystems; University of Rochester; University of Texas M. D. Anderson Cancer Center
- Class Amides; Antineoplastics; Benzene derivatives; Boronic acids; Ethers; Fluorinated hydrocarbons; Fluorobenzenes; Pyrimidines; Small molecules
- Mechanism of Action Interleukin 8A receptor antagonists; Interleukin 8B receptor antagonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Non-small cell lung cancer
- Phase I/II Colorectal cancer; Malignant melanoma; Myelodysplastic syndromes; Solid tumours
- No development reported Pancreatic cancer
Most Recent Events
- 29 Jan 2024 Syntrix Biosystems plans a phase II SYNERGY-201 trial for Prostate cancer (Metastatic-disease, Hormone refractory, Combination therapy) in the USA (PO) (NCT06228053)
- 28 Dec 2023 No recent reports of development identified for phase-I development in Pancreatic-cancer(Combination therapy, First-line therapy, Metastatic disease) in USA (PO, Pill)
- 31 Aug 2023 Chemical structure information added