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SX 682

Drug Profile

SX 682

Alternative Names: SX-682

Latest Information Update: 16 Feb 2024

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At a glance

  • Originator Syntrix Biosystems
  • Developer Boehringer Ingelheim; Bristol-Myers Squibb; National Cancer Institute (USA); Syntrix Biosystems; University of Rochester; University of Texas M. D. Anderson Cancer Center
  • Class Amides; Antineoplastics; Benzene derivatives; Boronic acids; Ethers; Fluorinated hydrocarbons; Fluorobenzenes; Pyrimidines; Small molecules
  • Mechanism of Action Interleukin 8A receptor antagonists; Interleukin 8B receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Non-small cell lung cancer
  • Phase I/II Colorectal cancer; Malignant melanoma; Myelodysplastic syndromes; Solid tumours
  • No development reported Pancreatic cancer

Most Recent Events

  • 29 Jan 2024 Syntrix Biosystems plans a phase II SYNERGY-201 trial for Prostate cancer (Metastatic-disease, Hormone refractory, Combination therapy) in the USA (PO) (NCT06228053)
  • 28 Dec 2023 No recent reports of development identified for phase-I development in Pancreatic-cancer(Combination therapy, First-line therapy, Metastatic disease) in USA (PO, Pill)
  • 31 Aug 2023 Chemical structure information added
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