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Emugrobart - Chugai Pharmaceutical

Drug Profile

Emugrobart - Chugai Pharmaceutical

Alternative Names: Emubrobart; Emubrobart - Roche; GYM-329; RG-6237; RG-70240​; RO-7204239

Latest Information Update: 03 Sep 2025

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At a glance

  • Originator Chugai Pharmaceutical
  • Developer Chugai Pharmaceutical; Roche
  • Class Antibodies; Monoclonal antibodies; Obesity therapies
  • Mechanism of Action Myostatin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Spinal muscular atrophy
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Spinal muscular atrophy
  • Phase II Facioscapulohumeral muscular dystrophy; Obesity
  • No development reported Neuromuscular disorders

Most Recent Events

  • 14 Aug 2025 Hoffmann-La Roche plans to initiate a phase I trial for Type 2 Diabetes Mellitus and Obesity (Treatment experienced) (SC) (NCT07137585)
  • 31 Jul 2025 Chugai Pharmaceuticals plans to file regulatory application for Obesity in the year 2028 or beyond (Chugai Pharmaceuticals pipeline, July 2025)
  • 05 May 2025 Phase-II clinical trials in Obesity in USA (SC) (NCT06965413)

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