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Nicotine degrading enzyme - Antidote Therapeutics

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Drug Profile

Nicotine degrading enzyme - Antidote Therapeutics

Alternative Names: ATI-3009; NicA2; NicA2-J1

Latest Information Update: 25 Apr 2023

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At a glance

  • Originator Antidote Therapeutics; The Scripps Research Institute
  • Developer Antidote Therapeutics; Minneapolis Medical Research Foundation; University of Minnesota
  • Class Drug withdrawal therapies; Enzymes; Recombinant proteins; Smoking cessation therapies
  • Mechanism of Action Oxidoreductases acting on CH-NH group donors modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Smoking withdrawal

Most Recent Events

  • 25 Apr 2023 Nicotine degrading enzyme is still in preclinical trials for Smoking withdrawal in USA (IV) (Antidote Therapeutics pipeline, April 2023)
  • 25 Apr 2023 Nicotine degrading enzyme is still in preclinical trials for Smoking withdrawal in USA (IV, Longer acting formulation) (Antidote Therapeutics pipeline, April 2023)
  • 28 Feb 2022 No recent reports of development identified for preclinical development in Smoking-withdrawal in USA (IV, Infusion)

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