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NBF 006

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Drug Profile

NBF 006

Alternative Names: NBF-006

Latest Information Update: 22 Jun 2024

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At a glance

  • Originator Nitto Biopharma
  • Class Antineoplastics; Small interfering RNA
  • Mechanism of Action Glutathione S-transferase pi expression inhibitors; Glutathione S-transferase pi inhibitors; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Colorectal cancer; Non-small cell lung cancer; Pancreatic cancer

Most Recent Events

  • 05 Apr 2024 Updated efficacy, adverse events and pharmacokinetics data from a phase I trial in Non-small cell lung cancer presented at the 115th Annual Meeting of the American Association for Cancer Research (AACR-2024)
  • 12 Mar 2024 Nitto BioPharma completes a phase-I clinical trials in Non-small cell lung cancer, Colorectal cancer, Pancreatic cancer (Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (IV) (NCT03819387)
  • 11 Oct 2023 Adverse events data from a phase I trial in Non-small cell lung cancer presented at the International Conference on Molecular Targets and Cancer Therapeutics 2023 (AACR-NCI-EORTC-2023)

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